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Dr. Constanze Lamprecht

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Freiburg Center for Interactive Materials and Bioinspired Technologies (FIT)
University of Freiburg
Georges-Köhler-Allee 105, 02.031
D-79110 Freiburg
phone: +49 761 203 95144
e-mail: constanze.lamprecht@physik.uni-freiburg.de

Institute of Physics, Experimental Polymer Physics
University of Freiburg
Hermann-Herder-Str. 3
D-79104 Freiburg
phone: +49 761 203 97782
e-mail: constanze.lamprecht@physik.uni-freiburg.de

 

Research

Topics: protein-lipid interactions, single molecule and single cell interactions, cancer cell evolution, drug delivery, regenerative cell growth
Techniques: force microscopy and spectroscopy, light microscopy, lipid bilayer membranes, native membranes, life cell experiments


Education

05/2007-12/2010 PhD Thesis in Biophysics, Johannes Kepler University Linz
(Advisor: Prof. P. Hinterdorfer)
05/2005-02/2007 Diploma Thesis in Superconductivity and Magnetism, Max-Planck-Institute for Chemical Physics of Solids
(Advisor: Dr. M. Nicklas, Prof. F. Steglich)
09/2000-08/2004 Studies of Physics, Technische Universität Dresden


 

Work Experience

Seit 09/2017 Postdoctoral Researcher, Carl-Zeiss-Fellow, Experimental Polymer Physics, University of Freiburg, Prof. G. Reiter
05/2015-05/2017 Postdoctoral Researcher, H2020 Marie Skłodowska-Curie Fellow, Institute of Biophysics, Johannes Kepler University Linz, Assis. Prof. A. Ebner
01/2012-04/2015 Postdoctoral Researcher, FP7 Marie Skłodowska-Curie Fellow, Institute for Material Science, Christian-Albrechts-University Kiel, Prof. C. Selhuber-Unkel
03/2011-12/2012 Scientific Writer, School of Pharmacy, University of Waterloo, Prof. M. Foldvari
01/2007-02/2011 Researcher, FP6 Marie Skłodowska-Curie Fellow, Institute of Biophysics, Johannes Kepler University Linz, Prof. P. Hinterdorfer
04/2005-12/2007 Research Assistant, SFB 463, High Pressure, Max-Planck-Institute for Physical Chemistry of Solids, Dr. M. Nicklas
01/2005-04/2005 Intern, R&D, EADS SPACE Transportation Bremen
09/2004-12/2004 Intern, R&D, EADS Military Munich


    

Publications

  • Biomedical Sensing with the Atomic Force Microscope. In: Springer Handbook of Nanotechnology. 4th Edition. Lamprecht, C; Strasser, J; Köhler, M et al.; Editor: Bhushan, B; Springer, Cham; 2017. In print.
    AND
    In: Nanotribology and Nanomechanics. 4th Edition. Editor: Bhushan, B; Springer, Cham; 2017. pp 135-173. ISBN: 9783319514321.
  • Leitner, M; Poturnayova, A; Lamprecht, C et al. Characterisation of the specific interaction between the DNA aptamer sgc8c and PTK7 on T-cells by biosensing AFM. Analytical and Bioanalytical Chemistry. 2017 Apr, 409(11): 2767-2776.
  • Lamprecht, C.*; Thaale, M.; Paulowicz, I. et al. A tunable scaffold of microtubular graphite for 3D cell growth. ACS Applied Materials & Interfaces. 2016 Jun, 8(24): 14980–14985.
  • Kadem, L F; Holz, M; Suana, K G; Li, Q; Lamprecht, C et al. Rapid Reversible Photoswitching of Integrin-Mediated Adhesion at the Single-Cell Level. Advanced Materials. 2016 Mar; 28(9): 1799-1802.
  • Henkel, B; Neubert, T; Zabel, S; Lamprecht, C et al. Photocatalytic properties of titania thin films prepared by sputtering versus evaporation and aging of induced oxygen vacancy defects. Applied Catalysis B. Environmental. 2016 Jan; 180: 362-371.
  • Herranz-Diez, C; Li, Q; Lamprecht, C et al. Bioactive compounds immobilized on Ti and TiNbHf: AFM-based investigations of biofunctionalization efficiency and cell adhesion. Colloids and Surfaces B: Biointerfaces. 2015 Dec; 136: 704-711.
  • Kadem, LF; Lamprecht, C; Purtov, J et al. Controlled Self-Assembly of Hexagonal Nanoparticle Patterns on Nanotopographies. Langmuir. 2015  Aug; 31(34): 9261–9265
  • Serfert, Y; Lamprecht, C; Tan, C-P et al. Characterization and use of β-lactoglobulin fibrils for microencapsulation of lipophilic ingredients and oxidative stability thereof. Journal of Food Engineering. 2014 Dec; 143: 53-61
  • Lamprecht C*; Hinterdorfer P; Ebner A. Applications of biosensing atomic force microscopy in monitoring drug and nanoparticle delivery. Expert Opinion on Drug Delivery. 2014 Aug; 11(8):1237-
  • Lamprecht, C*; Plochberger, B; Ruprecht V et al. A single- molecule approach to explore binding, uptake and transport of cancer cell targeting nanotubes. Nanotechnology. 2014 Mar; 25(12):125704
  • Serfert, Y; Kleinhans, R; Tan, C-P; Lamprecht, C et al. Einsatz von β-lactoglobulin-Fibrillen zur Herstellung mikrostrukturierter Trägersysteme. In: Produktgestaltung in der Partikeltechnologie - Band 6. Editors: Teipel, U; Weber, A. Fraunhofer Verlag, Fraunhofer ICT, Pfinztal, 2013. ISBN 978-3-8396-0537-0
  • Lamprecht, C*; Gierlinger, N; Heister, E et al. Mapping the intracellular distribution of carbon nanotubes after targeted delivery to carcinoma cells using confocal Raman imaging as a label-free technique. Journal of Physics: Condensed Matter. 2012 Mar; 24(16): 164206
  • Heister, E; Neves, V; Lamprecht, C et al.  Drug loading, dispersion stability, and therapeutic efficacy in targeted drug delivery with carbon nanotubes. Carbon. 2012 Feb; 50(2): 622-632
  • Ivanova, MV; Lamprecht, C; Laureiro, MJ; et al. Pharmaceutical characterization of solid and dispersed carbon nanotubes as nanoexcipients. International Journal of Nanomedicine. 2012 Jan; 7: 403-415. 
  • Rybak-Smith, MJ; Tripisciano, C; Borowiak-Palen, E; Lamprecht, C; Sim, RB. Effect of Functionalization of Carbon Nanotubes with Psychosine on Complement Activation and Protein Adsorption. Journal of Biomedical Nanotechnology. 2011 Dec; 7(6): 830-839.
  • Lamprecht, C; Huzil, TJ; Ivanova, MV; Foldvari, M. Non-Covalent Functionalization of Carbon Nanotubes with Surfactants for Pharmaceutical Applications - A Critical Mini-Review. Drug Delivery Letters. 2011 Sep; 1(1): 45-57.
  • Molecular recognition force spectroscopy. In: Molecular manipulation with atomic force microscopy. Willet N.; Lamprecht C.; Rankl C.; Rangl M et al.; Editors: Willet N. and Duwez A.-S. CRC Press, Boca Raton; 2011. ISBN: 9781439809662.
  • Exploring carbon nanotubes and their interaction with cells using atomic force microscopy. In: Carbon nanotubes for biomedical application. Lamprecht, C*; Ebner, A; Kienberger, F; Hinterdorfer, P; Editor: Klingeler, R.; Sim, R.B.; Springer Berlin; 2011. ISBN: 9783642148019
  • Heister, E; Lamprecht, C; Neves, V, et al. Higher dispersion efficacy of functionalized carbon nanotubes in chemical and biological environments. ACS Nano. 2010 Apr; 4(5): 2615–2626
  • Lamprecht, C; Liashkovich, I; Neves, V, et al. AFM imaging of functionalized carbon nanotubes on biological membranes. Nanotechnology. 2009 Oct; 20(43): 434001- 434007
  • Lamprecht, C; Danzberger, J; Lukanov, P, et al. AFM imaging of functionalized double-walled carbon nanotubes. Ultramicroscopy. 2009 Jul; 109(8): 899-906
  • Dulebo, A; Preiner, J; Kienberger, F; Kada, G; Rankl, C; Chtcheglova, L; Lamprecht, C; Kaftan, D and Hinterdorfer, P. Second harmonic atomic force microscopy imaging of live and fixed mammalian cells. Ultramicroscopy. 2009 Jul; 109(8): 1056-1060
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